About our therapy
A team of epilepsy experts at Mayo Clinic has recently demonstrated the ability to control seizures using targeted continuous electrical stimulation of epileptogenic brain tissue.* The therapy includes an optimization phase, during which EEG monitoring is used to analyze the brain's response to trial stimulation. During this optimization phase, stimulation parameters and location are established.
Patients that show a positive response to trial stimulation are candidates for subsequent implantation with a neurostimulator and electrodes targeting the identified regions, using the previously identified stimulation parameters.
Cadence is working closely with Mayo researchers to further develop this treatment and create a system that has been optimized to deliver the therapy. The system will then be assessed in clinical studies.
* Lundstrom BN, Van Gompel J, Britton J, Nickels K, Wetjen N, Worrell G, Stead M. (2016) Chronic Subthreshold Cortical Stimulation to Treat Focal Epilepsy.JAMA Neurol. +73(11):1370-1372.
Patients that show a positive response to trial stimulation are candidates for subsequent implantation with a neurostimulator and electrodes targeting the identified regions, using the previously identified stimulation parameters.
Cadence is working closely with Mayo researchers to further develop this treatment and create a system that has been optimized to deliver the therapy. The system will then be assessed in clinical studies.
* Lundstrom BN, Van Gompel J, Britton J, Nickels K, Wetjen N, Worrell G, Stead M. (2016) Chronic Subthreshold Cortical Stimulation to Treat Focal Epilepsy.JAMA Neurol. +73(11):1370-1372.